肖占刚教授-博导
作者:  发布时间:16-10-30 17:13:55   浏览次数: 次   来源:


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肖占刚(1983.2-),男,四川内江人,教授,博士生导师。2013年于香港中文大学生物医学院获得博士学位,2016年1月-迄今为西南医科大学教授,研究生导师。目前是Journal of Digestive Diseases and Hepatology; Clinics in Oncology; Journal of Veterinary and Dairy Science等期刊杂志的编委;亦获邀为Current Pharmaceutical Design; Tumor Biology; Journal of Medicinal Plant Research; Journal of Case Reports and Studies (JCRS);Oncology Letters等杂志的特邀审稿人;美国癌症协会(American Association for Cancer Research, AACR)和欧洲肿瘤免疫学会(European Academy for Tumor Immunology, EATI)会员。连续获得2016年国家自然科学基金青年基金,2017年国家自然科学基金面上项目资助。参编了国际著名论著Humana press出版的“Methods in molecular biology”;在Gastroenterology(影响因子:18.187);Cancer Research(影响因子:8.556);;Oncoimmunology(影响因子:7.644)等知名学术期刊上发表学术论文20多篇。研究方向

从事肿瘤分子生物学,表观遗传调控及靶向microRNA,lncRNA,肿瘤免疫checkpoints抗癌药物研发

工作经历

2016/01-迄今,西南医科大学,药学院,教授

2013/08-2015/12,香港中文大学,生物医学院,博士后研究员

2010/07-08,中国科学院, 水生生物研究所,助理研究员

代表论文(均为一作(^)或通信作者())

期刊论文

1. Zou C^, Zhao P^, Xiao Z^, Han X, Fu F, Fu L, γδ T cells in cancer immunotherapy. Oncotarget 2016 Accepted. (JCR Q1, 2015 IF: 5.008)

2. Hu T^, Chang Y^, Xiao Z^, Mao R, Tong J, Chen B, Liu GC, Hong Y, Hong-Lan Chen HL, Kong SY, Huang YM, Jin H, XiYang YB, MiR-1/G6PD is associated with the carcinogenic events of human cervical cancer infected with high-risk human papillomaviruses 16/18. Oncotarget 2016 Accepted. (JCR Q1, 2015 IF: 5.008)

3. Xiao Z, Shen J, Zhang L, Li L, Li MX, Hu W, Li ZJ, Cho CH†. The roles of histone demethylase UTX and JMJD3 (KDM6B) in cancers: current progress and future perspectives. Curr Med Chem. 2016 Jul 24. [Epub ahead of print]. (JCR Q2, 2015 IF: 3.455)

4. Zhu XY, Yan F, He B, Shen J, Xiao Z. A case report of non-secretory myeloma with renal failure. Clinics in Oncology. 2016 ,1, 1056

5. Zhu XY, Shen J, Xiao Z. Prothymosin alpha (ProTα) and thymosin Beta (Tβ): conserved immunerelated genes from teleost to mammals. Journal of Molecular Immunology. 2016 Accepted

6. Xu ZY, Shen J, Wang MH, Yi T, Yu YY, Zhu YX, Chen B, Chen JP, Li LF, Li MX, Zuo J, Jiang H, Zhou DX, Luan J, Xiao Z. Comprehensive molecular profiling of the B7 family of immune-regulatory ligands in breast cancer. OncoImmunology. 2016 Jul 11;5(8):e1207841. (JCR Q1, 2105IF:7.644)

7. Xiao Z, Shen J, Feng H, Liu H, Hu W, Wang Y, Huang R, Guo Q. Characterization of two thymosins as immune-related genes in common carp (Cyprinus carpio L.). Developmental & Comparative Immunology. 50(1): 29-37.2015. (JCR Q1, 2013IF:3.705)

8. Shen J^, Xiao Z^, Wu KK, Wang MH, To KF, Chen Y, Yang W, Li SM, Shin VY, Tong JH, Kang W, Zhang L, Li M, Wang L, Lu L, Chan RLY, Wong SH, Yu J, Chan MTV, Chan FKL, Sung JJY, Cheng ASL, Cho CH. Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis. Cancer Res. 75(4):1-12.2014. (JCR Q1, 2013IF:9.284)

9. Xiao Z, Chen Y. Small molecule targeting miR-34a for cancer therapy. Molecular and Cellular Oncology. 2(1). e977160. 2014.

10. Xiao Z, Li CH, Chan SL, Xu F, Feng L, Wang Y, Jiang JD, Sung JJ, Cheng CH, Chen Y. A small molecule modulator of the tumor suppressor miRNA-34a inhibits the growth of hepatocellular carcinoma. Cancer Res. 74(21):6236-47.2014. (JCR Q1, 2013IF:9.284)

11. Xiao Z, Ching Chow S, Li CH, Chun Tang S, Tsui SK, Lin Z, Chen Y. Role of microRNA-95 in the anticancer activity of Brucein D in hepatocellular carcinoma. Eur J Pharmacol. 728 (5):141-50.2014. (JCR Q2, 2013IF:2.684)

12. Xiao Z, Liu H, Fu JP, Hu W, Wang YP, Guo QL. Cloning of common carp SOCS-3 gene and its expression during embryogenesis, GH-transgene and viral infection. Fish Shellfish Immunol. 28(2):362-71.2010. (JCR Q1, 2013IF:3.034)

论著

1. Xiao Z, Chen Y, Identification of small molecule modulators of microRNA by library screening, Methods in molecular biology. Humana Press, Inc. NJ, U.S.A,2016 Accepted.

会议论文

1. Zhu YX, Xiao Z. JMJD3 serves as an oncogenic protein in gastric cancer. ICAD conference, 2016

2. Xiao Z, Chen Y. Ectopic expression of JMJD3 inhibits hepatocellular tumor growth by regulating DACH1 expression. AACR conference, 2014.

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