李明星-博士-硕导
作者:  发布时间:20-05-02 10:04:26   浏览次数: 次   来源:

 

 

博士,副教授,硕士研究生导师。

邮箱:star.lee@hotmail.com

办公室地址:四川省泸州市江阳区忠山路三段319西南医科大学忠山校区心源楼2


2009-1012年于四川大学华西医院生物治疗国家重点实验室攻读硕士学位,201612月获得香港中文大学生物医学博士学位。现任职西南医科大学药学院。主要研究领域包括:(1) 维生素D靶向胃癌肿瘤微环境治疗胃癌的机制研究;(2) 新型抗胃癌药物的开发与应用;(3)长链非编码RNA在胃癌中的机制研究。截止目前,已发表SCI论文20余篇,包括AutophagyActa Pharmaceutica Sinica BNanoscaleACS Materials & InterfacesLife SciencesCurrent Medicinal Chemistry等世界著名医学权威杂志,并参与编写1本领域专著。主持一项国家自然科学基金,参与一项国际自然科学基金面上项目与省部级课题。

代表性论文:

1. Yin J, Zhang H, Wu X, Zhang Y, Li J, Shen J, Zhao Y, Xiao Z, Lu L, Huang C, Zhang Z, Du F, Wu Y, Parham Jabbarzadeh Kaboli, Cho CH, Yuan D*, Li M*. CD44 inhibition attenuates EGFR signaling and enhances cisplatin sensitivity in human EGFR wild-type non-small-cell lung cancer cells. International Journal of Molecular Medicine. 2020(45):1783-1792.

2. Hu W, Chan H, Lu L, Wong KT, Wong SH, Li MX, Xiao ZG, Cho CH, Gin T, Chan MTV, Wu WKK*, Zhang L*. Autophagy in intracellular bacterial infection. Semin Cell Dev Biol. 2020; 101:41-50.

3. Xu Wu#, Jing Shen#, Zhangang Xiao, Jing Li, Yueshui Zhao, Qijie Zhao, Chi Hin Cho*, Mingxing Li*. An overview of the multifaceted roles of miRNAs in gastric cancer: Spotlight on novel biomarkers and therapeutic targets. Biochemical Pharmacology, 2019(163):425-439.

4. Wu X#, Hu W#, Lu L#, Zhao Y, Zhou Y, Li X, Li W, Zhang H, Xiao Z, Zhang L, Cho CH, Shen J*, Li MX*. Repurposing Vitamin D for Treatment of Human Malignancies via Targeting Tumor Microenvironment, Acta Pharmaceutica Sinica B. 2019;9(2):203–219.

5. Hu W#, Zhang L#, Li MX#, Shen J#, Liu XD, Xiao ZG, Wu DL, Ho IHT, Wu JCY, Cheung CKY, Zhang YC, Lau AHY, Ashktorab H, Smoot DT, Fang EF, Chan MTV, Gin T*, Gong W*, Wu WKK*, Cho CH*. Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through PDIA3 receptor in gastric epithelial cells. Autophagy 2019:1-19.

6. Li MX*, Li LF, Zhang L, Hu W, Shen J, Xiao Z, Wu X, Chan FL, Cho CH*. 1,25-Dihydroxyvitamin D3 suppresses gastric cancer cell growth through VDR- and mutant p53-mediated induction of p21. Life sciences. 2017; 179:88-97.

7. Li MX, Li LF, Zhang L, Xiao Z, Shen J, Hu W, Zeng Q, Cho CH*. Vitamin D and Cancer Stem Cells in the Gastrointestinal Tract. Current Medicinal Chemistry. 2017;24(9):918-927.

8. Li MX, Liu P, Gao G, Deng J, Pan Z, Wu X, Xie G, Yue C, Cho CH, Ma Y and Cai L*. Smac therapeutic Peptide nanoparticles inducing apoptosis of cancer cells for combination chemotherapy with Doxorubicin. ACS Applied Materials & Interfaces. 2015; 7(15):8005-8012.


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