吴旭-博士-硕导
作者:  发布时间:20-05-02 10:07:26   浏览次数: 次   来源:





博士,副教授,硕士研究生导师

E-mail: wuxulz@126.com

现就职西南医科大学药学院、川南医学转化研究院。主要研究领域包括:(1)药食两用中药、膳食多酚/多糖、肠道菌群;(2)多学科交叉中药研究;3基于临床样本及条件重编程技术的原代肿瘤细胞培养及应用、液体活检。发表SCI论文50余篇,其中第一及通讯作者论文20余篇,总IF>100;论文发表于包括Food Chemistry, Medicinal Research Reviews, Acta Pharmaceutica Sinica B, Journal of Ethnopharmacology, Nanoscale, Pharmacological Research国际同行评议杂志。目前为四川省药理学学会理事、四川省药理学学会肿瘤药理专业委员会委员。入选2020西南医科大学青年科技人才支持计划,主持1项国家级、1项省级、1项厅局级及4项横向合作项目,总研究经费大于150万元。


教育背景:

Ph.D. 香港中文大学生物医学学院,生物医学

M.Med. 中国中医科学院中药研究所,中药学

B.Sc. 成都中医药大学,中药学基地班


近年代表论著:

1. Xiaoxiao Wu; Shengpeng Wang ; Mingxing Li; Jing Li; Jing Shen; Yueshui Zhao; Jun Pang; Qinglian Wen; Meijuan Chen; Bin Wei; Parham Jabbarzadeh Kaboli; Fukuan Du; Qijie Zhao; Chi Hin Cho; Yitao Wang; Zhangang Xiao*; Xu Wu*; Conditional reprogramming: next generation cell culture, Acta Pharmaceutica Sinica B, 2020, https://doi.org/10.1016/ j.apsb.2020.01.011.

2. Anqi Wang; Mingxing Li ; Huimin Huang; Zhangang Xiao; Jing Shen; Yueshui Zhao; Jianhua Yin; Parham Jabbarzadeh Kaboli; Jiliang Cao; Chi Hin Cho; ; Yitao Wang;; Jing Li*; Xu Wu*; A review of Penthorum chinense Pursh for hepatoprotection: Traditional use, phytochemistry, pharmacology, toxicology and clinical trials, Journal of Ethnopharmacology, 2020, 251: 112569.

3. Yin, Jianhua; Ren, Wei ; Wei, Bin ; Huang, Huimin; Li, Mingxing; Wu, Xiaoxiao; Wang, Anqi; Xiao, Zhangang; Shen, Jing; Zhao, Yueshui; Du, Fukuan; Ji, Huijiao; Kaboli, Parham Jabbarzadeh; Ma, Yongshun; Zhang, Zhuo; Cho, Chi Hin; Wang, Shengpeng*; Wu, Xu*; Wang, Yitao; Characterization of chemical composition and prebiotic effect of a dietary medicinal plant Penthorum chinense Pursh., Food Chemistry, 2020, 319: 126568.

4. Xinhua Zhou, Anqi Wang, Liang Wang, Jianhua Yin, Li Wang, Lijun Di, Maggie Pui-Man Hoi, Luchen Shan*, Xu Wu* and Yuqiang Wang. A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer. Frontiers in Pharmacology. 2019, 10: 722.

5. Hongxun Tao#, Xu Wu#, Jiliang Cao, Yu Peng, Anqi Wang, Jin Pei, Jianbo Xiao, Shengpeng Wang*, Yitao Wang*, Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study. Medicinal Research Reviews. 2019, 39(5):1779-1850. (Featured article)

6. Chunyuan Zhang#, Xu Wu#, Yanfang Xian, Lin Zhu, Ge Lin*, and Zhi-Xiu Lin*. Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer’s Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats. Evidence-Based Complementary and Alternative Medicine. 2019, 4016323. https://doi.org/10.1155/2019/4016323.

7. Xu Wu#, Jing Shen#, Zhangang Xiao, Jing Li, Yueshui Zhao, Qijie Zhao, Chi Hin Cho*, Mingxing Li*. An overview of the multifaceted roles of miRNAs in gastric cancer: Spotlight on novel biomarkers and therapeutic targets. Biochemical Pharmacology. 2019, 163, 425-439.

8. Zhu Wang#, Jianhua Yin#, Mingxing Li, Jing Shen, Zhangang Xiao, Yueshui Zhao, Chengliang Huang, Hanyu Zhang, Zhuo Zhang, Chi Hin Cho, Xu Wu*. Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced ROS generation. Chinese Medicine. 2019, 14, 7.

9. Jing Jin#, Xu Wu#, Jianhua Yin, Mingxing Li, Jing Shen, Jing Li, Yueshui Zhao, Qijie Zhao, Jingbo Wu, Qinglian Wen, Chi Hin Cho, Tao Yi, Zhangang Xiao (2019). Identification of genetic mutations in cancer: challenge and opportunity in the new era of targeted therapy. Frontiers in Oncology, 9, 263.

10. Liyu Luo, Miaoxuan Fan, Haiyu Zhao, Mingxing Li, Xu Wu*, Wenyuan Gao*, Pharmacokinetics and bioavailability of the isoflavones formononetin and ononin and their in vitro absorption in Ussing chamber and Caco-2 cell models. Journal of Agricultural and Food Chemistry. 2018. 66 (11): 2917-2924.

11. Xu Wu, Shengpeng Wang, Junrong Lu, Yong Jing, Mingxing Li, Jiliang Cao, Baolin Bian, Changjiang Hu*. (2018). Seeing the unseen of Chinese herbal medicine processing (paozhi): advances in new perspectives. Chinese Medicine. 2018, 13(1): 4. (Featured article)

12. Xu Wu, SW Chan, Jiang Ma, Ping Li, PC Shaw, Ge Lin*. Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species. Journal of Ethnopharmacology. 2018, 210: 39-46.

13. Xu Wu#, Wei Hu#, Lan Lu#, Yueshui Zhao, Yejiang Zhou, Zhangang Xiao, Lin Zhang, Hanyu Zhang, Xiaobing Li, Wanping Li, Shengpeng Wang, Chi Hin Cho, Jing Shen*, Mingxing Li*, Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment. Acta Phamaceutica Sinica B, 2019, 9(2): 203-219.

14. Xu Wu, Shengpeng Wang, Mingxing Li, Anqi Wang, Yangyang Zhou, Peng Li*, Yitao Wang*. Nanocarriers for TRAIL delivery: driving TRAIL back on track for cancer therapy. Nanoscale. 2017, 9 (37) :13879-13904.

15. Xu Wu, Lin Zhu, Jiang Ma, Yang Ye, Ge Lin*. Adduct ion-targeted qualitative and quantitative analysis of polyoxypregnanes by ultra-high pressure liquid chromatography coupled with triple quadrupole mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2017, 145: 127-136.




>>更多
工作动态
  • 药学院党委组织召开2020年第一季度中心组(扩大)学...[详细]
  • 张福利研究员学术讲座[详细]
  • 药学院药理党支部参观护国战争纪念馆主题党日活动[详细]
  • 纽约霍夫斯特拉大学马莉教授来我院交流[详细]