陈禹，男，中共党员，博士。2013年于中国海洋大学获医学学士学位，2016年于山东大学获药学硕士学位，2020年于香港中文大学合成化学国家重点实验室获哲学博士学位。2020年9月至今为西南医科大学药学院专任教师，2023年3月-2024年2月为国家纳米科学中心访问学者及中国科学院青岛能源与过程研究所客座副研究员。研究兴趣：发展过渡金属催化C–H键活化、脱氢偶联反应、类药小分子合成及抗肿瘤药物化学。迄今在ACS Catalysis, Science China Chemistry, Chemical Communications, Organic Letters, Molecular Therapy-Oncolytics 等期刊发表SCI论文60余篇，其中通讯和一作10余篇。获得国家奖学金，山东大学药学院优秀学生，香港中文大学优秀教学助理，泸州市药学会优秀论文，四川省海外高层次留学人才，西南医科大学优秀兼职班主任等荣誉。指导硕士研究生、本科生毕业设计和大创项目，已培养毕业硕士生、本科生各3名，毕业生去往美国塔夫茨大学、山东理工大学等高校继续深造，或进入强生等知名药企。作为项目负责人目前主持科研项目3项，包括 (1)川大-泸州科技创新平台建设项目2022CDLZ-20，50万元；(2)西南医科大学校级项目2021ZKQN106，2万元；(3)西南医科大学科研启动经费0500040174，19万元。通讯地址：泸州市龙马潭区香林路西南医科大学药学院。E-mail: chenyu2021@swmu.edu.cn。
部分已发表学术论文：
1. Jiahong Su, Xingyue Wang, Sha Li, Xu Wu, Mingxing Li, Fukuan Du, Shuai Deng, Jing Shen, Yueshui Zhao, Zhangang Xiao,* and Yu Chen.* Synthesis and antitumor evaluation of glycyrrhetinic acid-dithiocarbamate hybrids. Arch. Pharm. 2025, 358, e2400421.
2. Liyao Tang,† Yan Zhang,† Jinrun Xu,† Qingfan Yang, Fukuan Du, Xu Wu, Mingxing Li, Jing Shen, Shuai Deng, Yueshui Zhao,* Zhangang Xiao,* and Yu Chen.* Synthesis of Oleanolic Acid-Dithiocarbamate Conjugates and Evaluation of Their Broad-Spectrum Antitumor Activities. Molecules, 2023, 28, 1414.
3. Mengyue Wang†, Yu Chen†, Cen Tang*, Recent Advances in Ligand Engineering for Gold Nanocluster Catalysis: Ligand Library, Ligand Effects and Strategies, Chem. Asian J., 2023, e202300463.
4. Yu Chen, Hairong Lyu, Yangjian Quan, Zuowei Xie.* Fe-Catalyzed Intramolecular B–H/C–H Dehydrogenative Coupling: Synthesis of Carborane-Fused Nitrogen Heterocycles. Org. Lett., 2021, 23, 4163–4167.
5. Peng Zhou, Yu Chen, Zuowei Xie.* Iron-Catalyzed Selective B–H Activation for 4/5-fold Methylation and Arylation of Carboranes. ACS Catal. 2022, 12, 8761–8767.
6. Yu Chen,† Yik Ki Au,† Yangjian Quan,* Zuowei Xie.* Copper Catalyzed/Mediated Direct B-H Alkenylation/Alkynylation in Carboranes. Sci. China Chem., 2019, 62, 74–79. 封面论文
7. Yu Chen, Yangjian Quan,* Zuowei Xie.* Ir-catalyzed Selective Dehydrogenative Crosscoupling of Aryls with o-carboranes via a Mixed Directing-Group Strategy. Chem. Commun., 2020, 56, 7001–7004.
8. Yu Chen, Yangjian Quan,* Zuowei Xie.* 8-Aminoquinoline as a bidentate traceless directing group for Cu-catalyzed selective B(4,5)-H disulfenylation of o-carboranes. Chem. Commun., 2020, 56, 12997–13000.
9. Yu Chen,† Fukuan Du,† Liyao Tang,† Jinrun Xu, Yueshui Zhao, Xu Wu, Mingxing Li, Jing Shen, Qinglian Wen, Chi Hin Cho, Zhangang Xiao.* Carboranes as unique pharmacophores in antitumor medicinal chemistry. Mol. Ther. - Oncolytics, 2022, 24, 400–416.
10. Yu Chen,† Qingfan Yang,† Jinrun Xu,† Liyao Tang, Yan Zhang, Fukuan Du, Yueshui Zhao, Xu Wu, Mingxing Li, Jing Shen, Ruiling Ding, Hongying Cao, Yu Du,* Qinglian Wen,* Zhangang Xiao.* PROTACs in Gastrointestinal Cancers, Mol. Ther. - Oncolytics, 2022, 27, 204-223.
11. Biao Cheng,† Yu Chen,† Peng Zhou, Zuowei Xie.* Rhodium-catalyzed sequential B(3)-, B(4)-, and B(5)-trifunctionalization of o-carboranes with three different substituents. Chem. Commun., 2022, 58, 629–632. 封面论文
12. Biao Cheng,† Yu Chen,† Zuowei Xie.* Iridium-Catalyzed Annulation of o‑Carboranyl Carboxylic Acids with Alkynes: Synthesis of Carborano-Isocoumarins. J. Org. Chem. 2021, 86, 12412–12418.
13. Yao Zhang,† Yu Chen,† Yue Wan,† Yueshui Zhao, Qinglian Wen, Xiaolong Tang, Jing Shen, Xu Wu, Mingxing Li, Xiang Li, Jing Li, Wanping Li,* Zhangang Xiao,* Fukuan Du.* Circular RNAs in the Regulation of Oxidative Stress. Front. Pharmacol., 2021, 12, 697903.
14. Qingfan Yang,† Yu Chen,† Rui Guo, Yalan Dai, Liyao Tang, Yueshui Zhao, Xu Wu, Mingxing Li, Fukuan Du, Jing Shen, Tao Yi*, Zhangang Xiao*, Qinglian Wen*. Interaction of ncRNA and epigenetic modifications in gastric cancer：Focus on histone modification. Front. Oncol., 2022, 11, 822745.
15. Yu Chen,† Li Su,† Xinying Yang, Wenyan Pan, Hao Fang.* Enantioselective Synthesis of 3,5-disubstituted Thiohydantoins and Hydantoins. Tetrahedron, 2015, 71, 9234–9239.
