药学（药物化学）-易东副教授-硕导
易东，西南医科大学药学院药物化学教研室副主任，副教授（博士，学术型/专业型研究生导师），毕业于中国科学院大学成都生物研究所药物化学专业。于药物化学教研室承担研究生、本专科各专业的教学工作，主要讲授《药物合成反应》、《高等有机化学》、《药物化学专论》等专业课程。
研究方向：新药创制（神经退行性疾病治疗、抗肿瘤药物研发等）；绿色精准合成（可见光催化、氮杂环卡宾催化、杂环化学等）。
招生专业：100701药物化学（学术型硕士）；105500药学硕士（药物合成与工艺优化，专业型硕士）
主持项目：国家自然科学基金1项、四川省自然科学基金项目1项、四川省科技计划联合创新专项项目1项、泸州市人民政府-西南医科大学科技战略合作项目2项、西南医科大学应用基础研究项目3项、功能有机分子化学国家重点实验室开放基金1项、核医学与分子影像四川省重点实验室开放基金1项等。
科研成果：发表SCI论文37余篇，其中第一作者或通讯作者发表SCI论文26篇，部分代表性论文如下：
1. Metal-free photocatalytic [4+2] annulation of acrylamides with 2-benzyl-2-bromocarbonyls to assemble tetralin-1-carboxamides. Chinese Journal of Chemistry 2024, 42, 157.
2. Synergistic Brønsted base/photoredox-catalyzed three-component coupling with malonates to synthesize δ-hydroxy esters and δ-keto esters. Chinese Journal of Chemistry 2024, 42, 957.
3. Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters, aryl isothiocyanates, amines and cyclic ethers. Chinese Chemical Letters 2024, 35, 109107.
4. Additive-free aerobic oxidative difunctionalization of alkenes with P4S10 and alcohols to access
β-hydroxy phosphorodithioates. Green Chemistry 2023, 25, 10678.
5. Photoredox-catalyzed three-component 1,2-cyanoalkylpyridylation of styrenes with nonredox-active cyclic oximes. The Journal of Organic Chemistry 2023, 88, 16410.
6. Photocatalytic [2+2+m] cyclization of 2-cyanoaryl acrylamides with 2-bromocarbonyls involving C(sp3)-H functionalization. Advanced Synthesis & Catalysis 2023, 365, 4513.
7. Photoredox-neutral ring-opening pyridylation of cyclic oximes via phosphoranyl radical-mediated N–O/C–C bond cleavages and sequential radical-radical coupling. Chinese Chemical Letters, 2023, 34, 107822.
8. Chemodivergent photocatalytic access to 1-pyrrolines and 1-tetralones involving switchable C(sp3)–H functionalization. Frontiers in Chemistry 2022, 10, 1058596.
9. Indole and pyrrole derivatives as pre-photocatalysts and substrates in the sulfonyl radical-triggered relay cyclization leading to sulfonylated heterocycles. Organic Letters 2022, 24, 10, 2014.
10. Hydrogen bond serving as a protecting group to enable the photocatalytic [2+2] cycloaddition of redox-active aliphatic-amine-containing indole derivatives. Chemical Communications 2022, 58, 3194.
11. Photocatalytic deoxygenative carboimination towards functionalized pyrrolines by using unstrained γ,δ-unsaturated oximes. Advanced Synthesis & Catalysis, 2021, 363(8), 2110.
12. Nitrogen-radical-triggered trifunctionalizing ipso-spirocyclization of unactivated alkenes with vinyl azides: a modular access to spiroaminal frameworks. Advanced Synthesis & Catalysis, 2021, 363(8), 3762.
13. Copper-catalyzed aerobic oxidative cleavage of unstrained carbon-carbon bonds of 1,1-disubstituted alkenes with sulfonyl hydrazides. Chinese Journal of Chemistry 2021, 39(4), 859.
14. Ti-catalyzed regioselective ring-opening alkynylation of epoxides with haloalkynes. Tetrahedron Letters 2021, 85, 153461.
15. Photocatalytic intramolecular [2+2] cycloaddition of indole derivatives via energy transfer: a method for late-stage skeletal transformation. ACS Catalysis 2020, 10, 10149.
16. Organo-photoredox catalyzed defluoroacetalation of α-trifluoromethyl alkenes for synthesis of masked γ,γ-difluoroallylic aldehydes. Tetrahedron Letters 2020, 61(39), 152369.
17. Preparation of pyrido[1,2-c][1,2,4]triazole-based π-conjugated triazene as a Fe3+ ion fluorescent sensor. Chinese Chemical Letters 2019, 30, 1059.
工作地址：四川省泸州市龙马潭区香林路1段1号西南医科大学药学院药物化学教研室（弘润楼），邮编646000。
E-mail: yidong@swmu.edu.cn。
