
郝娜,博士,西南医科大学药学院药物化学教研室,副教授,硕士研究生导师。毕业于四川大学生物医学工程专业,日本理化学研究所访问学者。承担多门本科生和研究生课程,包括《天然药物化学》、《临床药物化学》、《药物分子设计》、《药物化学专论》。
研究方向:过渡金属催化方法学、多功能药物载体材料与系统的构建。
科研成果:近5年以第一作者或通讯作者发表部分代表性SCI论文如下:
1. Regio- and Stereoselective Hydroalkynylation of Internal Alkynes with Terminal Alkynes by Half-Sandwich Rare-Earth Catalysts. Journal of the American Chemical Society, 2025, 147, 6149−6161.
2. Novel NIR fluorescent probe IR-546 inhibits melanoma through the AKT/GSK3β/β-catenin pathway, Molecular Medicine, 2025, 31, 226.
3. Divergent Synthesis of Multi-Substituted Aminotetralins via [4+2] Annulation of Aldimines with Alkenes by Rare-Earth-Catalyzed Benzylic C(sp3)-H Activation. Angewandte Chemie International Edition. 2024, e202318203.
4. Catalytic C–H alkynylation of benzylamines and aldehydes with aldimine-directing groups generated in situ. Chemical Communications, 2023, 59, 6355-6358.
5. Photocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radicalmediated C–C and C–CN bond cleavage, Organic Chemistry Frontiers, 2022, 9, 2129-2134.
6. Redox-sensitive polymeric micelles with aggregation-induced emission for bioimaging and delivery of anticancer drugs,Journal of Nanobiotechnology, 2021, 19, 14.
7. Iron-catalyzed para-selective C–H silylation of benzamide derivatives with chlorosilanes, Organic Chemistry Fronteiers, 2021, 8, 2442-2448.
8. Anti-soiling performance of lotus leaf and other leaves after prolonged outdoor exposure, ACS Applied Materials & Interfaces, 2020, 12, 53394-53402.
9. Silver-catalyzed regioselective deuteration of (hetero) arenes and a-deuteration of 2-alkyl azaarenes, RSC Advances, 2020, 10, 25475-25479.
主持项目:
1. 四川省自然科学基金项目1项、泸州市-西南医科大学科技战略合作项目1项、西南医科大学应用基础研究项目4项、国家重点实验室开放基金1项、核医学与分子影像四川省重点实验室开放基金1项等。
通讯地址:泸州市龙马潭区香林路1段1号西南医科大学城北校区弘润楼
E-mail:haona@swmu.edu.cn