林燕简介

林燕，1984年11月生，毕业于四川大学华西药学院，博士，副教授，现为西南医科大学药学院药剂学教研室教师。主要研究方向为基于临床需求的药物新剂型与新技术研究，主持省级科研课题1项、厅局级课题2项；参与国家自然科学基金项目2项（主研），国家十一五“新药创制重大科技专项”子课题2项，获得授权国家发明专利4项；获重庆市科技进步二等奖2项，四川省科技进步奖三等奖1项，四川省医学科技奖1项。

专利：

1. 氨基葡萄糖衍生物作为小分子药物肾靶向修饰基团的用途，中国，ZL102977175A

2. 一种注射用炎琥宁冻干制剂及其制备方法，中国，ZL104606148A

3. 一种焦磷酸盐化胆固醇及其制备方法和用途，中国，ZL 201710873788.0

4. pH敏感靶向聚合物胶束PPi-Far-PMs及其制备方法和应用，中国，ZL201910283048.0

发表论文（SCI）

1. Yan Lin^#, Yujie Wan^#, Xingjie Du^#, Jian Li^#, Jun Wei, Ting Li, Chunhong Li, Zhongbing Liu, Meiling Zhou*, Zhirong Zhong*. TAT-Modified Serum Albumin Nanoparticles for Sustained-Release of Tetramethylpyrazine and Improved Targeting to Spinal Cord Injury. Journal of Nanobiotechnology. 2021 Jan 21;19(1):28.

2. Yan Lin, Yanping Li, Xiaohong Wang, Tao Gong, Ling Zhang, Xun Sun. Targeted drug delivery to renal proximal tubule epithelial cells mediated by 2-glucosamine, Journal of controlled Release.

3. Ting Li ^a,c,#, Zhongbing Liu ^a,#, Jingxuan Wang ^a,#, Haoming Ye ^a,#, Yujie Wan ^a,#, Xingjie Du ^a, Xiaoduan Sun ^a, Meiling Zhou ^b, Yan Lin ^a*, Pei Jing ^b,*, Zhirong Zhong ^a,*. Nanoformulated metformin enhanced the treatment of spinal cord injury. Chemical Engineering Journal, 2022, 446: 137227.

4. Ting Li ^a,c,#, Pei Jing^b,#, Lingling Yang ^a,#, Yujie Wan ^a,#, Xingjie Du ^a, Jun Wei ^a, Meiling Zhou ^b, Zhongbing Liu ^a, Yan Lin^a,*, Zhirong Zhong ^a,*. CAQK modification enhances the targeted accumulation of metformin-loaded nanoparticles in rats with spinal cord injury. Nanomedicine-Nanotechnology Biology and Medicine. 2022, 41: 102526.

5. Lin Chen ^1,2#, Yan Lin ^1#, Zijun Zhang ^1#, Ruisheng Yang¹, Xiaosheng Bai¹, Zhongbing Liu¹, Zhongling Luo¹, Meiling Zhou ³*, Zhirong Zhong ¹*. A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer. Journal of Nanobiotechnology. 2021 Oct 19;19(1):329.

6. Zhenyu Chen^#, Zhongling Luo^#, Jiayao Lyu^#, Jianxin Wang, Zhongbing Liu, Jun Wei, Yan Lin*, Zhirong Zhong*. Preparation and Formulation Optimization of Methotrexate-loaded Human Serum Albumin Nanoparticles Modified by Mannose. Current medicinal chemistry. 2021, 28(24): 5016-5029.

7. Xiaohong Wang, Yan Lin, Yingchun Zeng, Xun Sun, Tao Gong, Zhirong Zhang. Effects of mycophenolic acid-glucosamine conjugates on the base of kidney targeted drug Delivery, International Journal of Pharmaceutics.

8. Yan Lin, Xun Sun, Tao Gong, Zhi Rong Zhang. Prednisolone succinate glucosamine conjugate: Synthesis, characterization and in vitro cellular uptake by kidney cell lines, Chinese Chemical Letters.

9. Yan Lin, Xun Sun, Tao Gong, Zhi Rong Zhang. synthesis and in vivo distribution of 2-deoxy-2-amino diglucose-prednisolone conjugate (DPC), Chinese Chemical Letters.

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